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8 Best Hybrid Strains to Try in 2022
sativa and indica leaf, trophy on a purple/green gradient background
Hybrid strains are made by crossing sativa strains with indica strains. In fact, most cannabis strains are hybrids, as there are very few pure sativa or indica strains. In fact, the term “strains” is inaccurate, as even a particular variety from a specific part of the world can grow in both sativa-like and indica-like ways, depending on the environment it was grown in.

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Sativa strains are known for their energizing effects, while indicas are known for being calming. The full picture is more complicated, but most people associate invigoration with sativas and relaxation with indicas. Then, what are the effects of hybrid strains that combine sativa and indica lineage?

In the past, hybrid varieties of cannabis were thought to have both energizing and relaxing effects, usually one followed by the other. However, as we now know, it’s what cannabinoids and terpenes are in the plant that count when it comes to effect. “Sativa” and “indica” distinctions are meaningless when it comes to its effects.

Still, there is some value in looking at what varieties have been used to create a hybrid and what traits breeders look for when creating them. Learn more about hybrid cannabis strains as we present our top eight list for 2022.

White Widow
White Widow has diverse global origins as the offspring of a Brazilian sativa and Indian indica. The hybrid contains a fairly balanced ratio of cannabidiol (CBD) to tetrahydrocannabinol (THC). For many people, this 1:1 ratio is ideal and activates the synergistic entourage effect, which in turn may exert potency over conditions like chronic pain and anxiety.

Gorilla Glue
Gorilla Glue is a powerhouse hybrid strain that also goes under the names Original Glue, Gorilla Glue #4 and GG4. Euphoria and deep relaxation are likely effects of this THC-heavy (20%) strain that has won multiple Cannabis Cup awards. Earthy and a bit sour, Gorilla Glue is a blend of Chem’s Sister, Sour Dubb and Chocolate Diesel.

OG Kush
The Sunshine State takes credit for the development of OG (Original Gangster) Kush in the 1990s. Cultivators in Florida crossed Chemdawg, Lemon Thai and Hindu Kush to create this high-THC (18%) and no-CBD (0%) strain. Lemony OG Kush is reputed to produce a head high along with stress-relieving effects for the body.

Chiquita Banana
Fans of OG Kush might like Chiquita Banana, a potential option for people seeking deep therapeutic effects. Chiquita Banana crosses OG Kush with Banana, and the result is a motherlode of THC: 26%. Novices beware and avoid this strain (especially in the form of super-potent marijuana edibles). There’s not a drop of CBD in this hybrid, but there is a good amount of limonene, a terpene reported to have antioxidant and anti-inflammatory properties.

Bruce Banner #3
Any cannabis strain named for a superhero’s alter ego must be potent, and Bruce Banner #3 definitely is. Not quite as THC-heavy as Chiquita Banana at 20%, this hybrid strain nonetheless packs a punch. Bred from OG Kush and Strawberry Diesel, Bruce Banner #3 is known for its fast-acting effects which lean towards invigorating. This motivating strain is popular among consumers who have a full plate of tasks to accomplish.

Sour Space Candy
If you’re looking for a CBD-dominant hybrid, Sour Space Candy makes a strong contender. With a 16% concentration of CBD and just 1% THC, Sour Space Candy could relax you without getting you high. First bred in Oregon, the hybrid strain includes the parentage of Sour Tsunami and Early Resin Berry. Cannabis plants of this strain yield colorful buds and a slightly sour citrus profile.

Cherry Pie
Breed Granddaddy Purple with F1 Durb and you’ve got a hybrid strain that tastes like sweet and sour cherries. Some people attribute a case of the giggles to this euphoric strain, while others simply unwind with its balance of energizing and calming effects. The THC content is moderate (16%) but still high for a novice cannabis consumer.

Skunk #1
Skunk #1 has a long history dating back to the 1970s. The hybrid is genetically diverse with a blend of origins including Afghani, Acapulco Gold and Colombian Gold. The munchies are a stereotypical effect of marijuana, but it’s no myth that Skunk #1 might make you crave a hearty snack. Along with euphoric energy, hunger is one of the most commonly reported effects of Skunk #1.

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Frequently Asked Questions
What is the strongest hybrid strain?

Bruce Banner #3 and Chiquita Banana are two of the strongest hybrid cannabis strains, as they have been developed with THC in mind. Hybrids are often developed with vigor, pest resistance and cannabinoid content in mind, with many being developed specifically for their THC or CBD content.A strong hybrid strain is often characterized by high or mid-range THC content and a wide array of other cannabinoids and terpenes.

However, cannabis is a natural substance with lots of variation, so varieties that usually have moderate THC content may on occasion have high THC content.

Which strain is better, hybrid or indica?
The better strain is always the one that works better for you. Plus, it can be difficult to differentiate between hybrids and indicas, and in some instances there might actually be little-to-no difference at all! In fact, some indica-leaning strains like Wedding Cake and Girl Scout Cookies (GSC) fall under the hybrid umbrella because they are not pure. The same is true of many sativa strains, like Blue Dream, which are not 100% sativa. Experiment with different strains to see which one helps you meet your health and wellness goals.

Should you try a hybrid strain if you’re a beginner?
If you’re a beginner, you might want to consider a CBD-dominant hybrid strain. Starting with a hybrid strain that tips more toward THC dominance can be risky and more likely to lead to side effects. Speak with a qualified budtender at a licensed dispensary to see which marijuana strain could work best for you as a beginner.

Experience the benefits of hybrid strains with a medical marijuana card. Our doctors are here to meet with you and help you apply for your MMJ card today.