Terpineol, the Fragrant Nectar of Kings

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What is Terpineol?

Terpineol is a terpene, a type of organic compound that is commonly found in many plants, including cannabis, pine trees, and lilacs. It can also smell sweet, fresh and a bit like lilacs or roses, and quite different to lavender (linalool). It is a colorless liquid with a floral, piney scent and a mild, sweet taste. Terpineol is often used as an ingredient in perfumes, soaps, and other cosmetics due to its pleasant aroma. In addition to its use in the fragrance industry, terpineol has been found to have potential therapeutic benefits, such as anti-inflammatory and analgesic effects. It may also have antifungal and antibacterial properties. In cannabis, it is believed to contribute to the herb’s sedative and relaxing effects.


What Are the Benefits of Terpineol?

Terpineol is a terpene found in cannabis and a variety of other plants. It has been shown to have a range of potential benefits and uses, including:

Aromatherapy
Terpineol is commonly used in aromatherapy due to its pleasant floral scent and potential therapeutic effects. It can be inhaled through a diffuser, added to bath water, or used in massage oils or lotions. When inhaled, it can help promote relaxation, relieve stress, and improve mood. It is also thought to have decongestant properties that can help relieve respiratory issues. Additionally, some people use it in aromatherapy to help improve focus and mental clarity. However, it is important to note that scientific research on the specific aromatherapeutic effects of terpineol is limited, and more studies are needed to fully understand its potential benefits.


Listen as Alex J. discusses linalool. See her other videos on our YouTube channel.


Pain relief
There is limited research on the pain-relieving effects of terpineol specifically, but some studies suggest that it may have analgesic (pain-relieving) properties.

One study published in the journal Phytotherapy Research in 2013 found that terpineol, when administered in combination with the cannabinoid cannabidiol (CBD), was effective in reducing pain and inflammation in a rat model of arthritis. The authors of the study suggested that terpineol may enhance the anti-inflammatory and pain-relieving effects of CBD.

Another study published in the Journal of Ethnopharmacology in 2017 found that a terpineol-rich extract of the plant Lippia alba had significant analgesic effects in a mouse model of neuropathic pain. The authors of the study suggested that terpineol may exert its analgesic effects through modulation of the GABAergic system, which is involved in the regulation of pain signaling in the nervous system.

More research is needed to fully understand the mechanisms through which terpineol may offer pain relief, but these preliminary findings suggest that terpineol may have potential as a natural pain-relieving agent.


Anti-inflammatory properties
Terpineol has been shown to have anti-inflammatory properties. Inflammation is a natural response of the body’s immune system to injury, infection, or foreign substances. However, chronic inflammation can lead to tissue damage and is associated with a number of diseases, including arthritis, asthma, and cardiovascular disease.

Research has suggested that terpineol can reduce inflammation by inhibiting the activity of pro-inflammatory cytokines, molecules that play a key role in the inflammatory response. By blocking the production of these cytokines, terpineol may help reduce inflammation and the associated tissue damage.

In addition to inhibiting cytokines, terpineol has been shown to inhibit the activity of enzymes involved in the production of inflammatory molecules, such as prostaglandins and leukotrienes. By reducing the levels of these inflammatory molecules, terpineol may help alleviate inflammation and associated symptoms.

It’s worth noting that much of the research on terpineol’s anti-inflammatory properties has been conducted in animal and in vitro (test tube) studies, and further research is needed to determine the effects of terpineol on human inflammation.


The lime blossom flower, which contains high levels of terpineol, was traditionally used to treat colds and called the “nectar of kings” for its scent and therapeutic benefits.


Sedative effects
Terpineol has been reported to have sedative effects, but the research on its effectiveness as a sedative is limited. Some studies have suggested that terpineol may have sedative effects in animals, but more research is needed to determine its effectiveness in humans. Additionally, the sedative effects of terpineol may vary depending on the individual and the method of administration.


Potential anti-cancer effects
Research has shown that terpineol may have potential anti-cancer properties. In vitro studies have suggested that terpineol may induce apoptosis (programmed cell death) in cancer cells, inhibit tumor growth, and suppress cancer cell migration and invasion.

A study published in the journal Anticancer Research in 2014 reported that terpineol had cytotoxic effects on human colon cancer cells, inhibiting their growth and inducing cell death. Another study published in the same journal in 2016 found that terpineol inhibited the growth of breast cancer cells and induced apoptosis.


What Are the Potential Risk/Side Effects?

Terpineol is generally recognized as safe for use in food and cosmetics, but some people may experience skin irritation or allergic reactions when exposed to it. Ingesting large amounts of terpineol can also cause nausea, vomiting, and respiratory problems. Additionally, some studies have suggested that inhaling terpineol vapor may cause lung irritation, although more research is needed to confirm these findings. As with any substance, it is important to use terpineol in moderation and to consult with a healthcare provider before using it for therapeutic purposes.


Strains Dominant in Terpineol

Local Cannabis Strains in Jacksonvillle: Double Up Mints, Pineapple Hash, Jungle Spice, Orange Bubblegum, Kush Mountain, Golden Nugget

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If you have questions about Limonene or other terpenes, speak to our Medical Marijauna Specialists at your next appointment. They can help guide you in the right direction when it comes to picking strains or products at your favorite dispensary. Give us a call at (904) 586-0041 or submit a short application today!

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