There is some evidence that suggests that cannabis may be effective in treating some of the symptoms of sickle cell disease, but more research is needed to fully understand its potential benefits and risks. Sickle cell anemia is a genetic blood disorder that causes red blood cells to form a sickle shape, leading to reduced blood flow, pain, and other complications. Pain is a common symptom of sickle cell anemia, and it can be severe and difficult to manage.
In a study spanning just over 31,000 patient days, 232 adult SCD patients experienced chronic pain on more than 54% of total days [1]. Acute, painful episodes are a characteristic feature of sickle cell that require hospitalization, impair quality of life, and impact patient survival [2]. Opioids are the base for pain management in sickle cell, but high doses of opioids are required and are associated with adverse effects including pruritus, tolerance and opioid-induced hyperalgesia (OIH) [3,4].
Sickle cell anemia is a chronic condition that requires long-term management. The goal of treatment for sickle cell anemia is to relieve symptoms, prevent complications, and improve quality of life. The following are some of the common treatments for sickle cell anemia:
Bone marrow transplantation (BMT) is a complex and potentially life-saving procedure that is used to treat a variety of conditions, including sickle cell anemia. The mortality rate of bone marrow transplants range from 1 to 30%, depending on a number of factors, including the patient’s age, overall health, the type of transplant, and the presence of any complicating factors, such as infections or other medical conditions.
Studies have shown that cannabis can be effective in reducing pain, improving sleep, and reducing anxiety and depression. Additionally, some preclinical studies have suggested that the endocannabinoid system, which is the system in the body that interacts with cannabinoids like those found in cannabis, may play a role in regulating pain and inflammation in sickle cell anemia.
However, it is important to note that while cannabis may be effective in treating some of the symptoms of sickle cell anemia, it is not a cure for the disease. Additionally, the use of cannabis, especially in its smoked form, is associated with several potential side effects and health risks including respiratory problems, increased heart rate, and impaired cognitive and motor function [6,7,8] .
If you have sickle cell anemia and are considering using cannabis for symptom relief, it is important to consult with a healthcare provider who is familiar with both the disease and the use of cannabis. They can help you make an informed decision based on your individual needs and circumstances.
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The COVID-19 pandemic has taken a serious toll on mental health, compounding mental issues such as anxiety. Intending to manage anxiety, the number of people turning to cannabis – otherwise referred to as marijuana – is rising fast. According to new research from the Journal of Addictive Diseases, medical cannabis users have upped their use by an average of 91 percent. The increase is evident since the beginning of the coronavirus pandemic.